Fomepizole, Infusion

What are other names for this medicine?

Type of medicine: antidote

Generic and brand names: fomepizole, infusion; Antizol

What is this medicine used for?

This medicine is given by IV infusion to treat ethylene glycol (such as antifreeze) or methanol (such as window wiper fluid) poisoning.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, the healthcare provider should know if you have ever had:

• an allergic reaction to any medicine
• kidney disease

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

The infusion is given by a healthcare provider.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: nausea, vomiting, dizziness.

What should I watch out for?

You will be carefully monitored while receiving this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Severe vomiting, seizures, slow or fast heartbeat, uncontrolled eye movements, trouble urinating.

Other: Pain at the spot where injection is given, headache, nausea, vomiting, diarrhea, dizziness, drowsiness, bad taste in the mouth, mild rash, hiccups, change in sense of smell, stomach pain.

What products might interact with this medicine?

No significant drug interactions have been reported.

Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

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